Total costs associated with replicating and non-replicating smallpox vaccines
نویسندگان
چکیده
منابع مشابه
Repair replication in replicating and non-replicating DNA after irradiation with UV light.
Ultraviolet light induces more pyrimidine dimers and more repair replication in DNA that replicates within 2 to 3 hr of irradiation than in DNA that does not replicate during this period. This difference may be due to special conformational changes in DNA and chromatin that might be associated with semiconservative DNA replication.
متن کاملNon-replicating Toxoplasma gondii reverses tumor-associated immunosuppression
We examined the efficacy of using attenuated non-replicating Toxoplasma gondii uracil auxotrophs that can be safely delivered as anticancer immunotherapeutics. This strategy exerted remarkable therapeutic activity in murine models of melanoma and ovarian carcinoma, and holds broad potential for the development of novel, highly effective anticancer vaccines.
متن کاملActivity of Trifluoperazine against Replicating, Non-Replicating and Drug Resistant M. tuberculosis
Trifluoperazine, a known calmodulin antagonist, belongs to a class of phenothiazine compounds that have multiple sites of action in mycobacteria including lipid synthesis, DNA processes, protein synthesis and respiration. The objective of this study is to evaluate the potential of TFP to be used as a lead molecule for development of novel TB drugs by showing its efficacy on multiple drug resist...
متن کاملDendritic Cell Targets for Self-Replicating RNA Vaccines
Vaccination is the cornerstone for controlling many pathogen infections [1-8], and is also under scrutiny for cancer Immunoprophylaxis/immunotherapy [9,10]. Induction of both antibody and cell-mediated immune (CMI) defences is preferable for ensuring robust immune defence against most pathogen infections, although defence against certain pathogens may require a more dominant CMI response as exe...
متن کاملReplicating Milgram
The author conducted a partial replication of Stanley Milgram’s (1963, 1965, 1974) obedience studies that allowed for useful comparisons with the original investigations while protecting the well-being of participants. Seventy adults participated in a replication of Milgram’s Experiment 5 up to the point at which they first heard the learner’s verbal protest (150 volts). Because 79% of Milgram’...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Global Security: Health, Science and Policy
سال: 2016
ISSN: 2377-9497
DOI: 10.1080/23793406.2016.1171944